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Together, these data posit that the SDN-1/TRP-2 axis controls APTF-2-dependent regulation of PZ germ cell number by GLP-1, likely through modulation of Ca 2+ levels

38:1730-1735 [PMC free article: PMC4542276] [PubMed: 26180105] 143

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Toxicokinetic analysis showed a dose-dependent increase in plasma rotigotine concentrations

Studies report substantial weight loss, with some participants achieving double-digit to ~2030% body weight reduction over time in higher-dose groups (based on Phase 2/3 data trends)

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