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Lang T, Croal B

A comprehensive review in Nature Reviews Disease Primers described B12 deficiency as a significant and underrecognized public health concern, particularly among older adults, individuals with gastrointestinal conditions, and those following plant-based diets (Green et al., Nat Rev Dis Primers , 2017)

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Investigating Mechanisms in Humans: While preclinical studies have elucidated many molecular pathways, further research is needed to confirm if these mechanisms operate identically or with similar magnitude in human physiology