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Wegovy (semaglutide): a new weight loss drug for chronic weight management: [accessed 20 March 2026] BMJ (2025)

A 2011 study investigated the potential lipotropic effects of certain plant products in rats and found the following may have weight loss benefits: choline betaine myoinositol methionine carnitine magnesium niacin pantothenate folates Other substances in plant foods such as fatty acids, fiber, and flavonoids may also have lipotropic effects

Targeted modification of the cationic anticancer peptide HPRP-A1 with iRGD to improve specificity, penetration, and tumor-tissue accumulation

The most common side effects include: Cardiovascular effects : Increased heart rate and blood pressure (occurs in most users), palpitations, chest pain in rare cases Sleep disturbances : Insomnia or difficulty staying asleep (especially if taken late in the day) Dry mouth : Nearly universal complaint among users Gastrointestinal issues : Constipation, diarrhea, or nausea Neurological effects : Dizziness, headaches, restlessness, tremors Mood changes : Irritability, anxiety, or in rare cases, euphoria Serious side effects are uncommon but possible, including primary pulmonary hypertension (a potentially fatal lung condition), heart valve problems, and psychological dependence

2.1 Dysbiosis of intestinal flora A reduction in the abundance and diversity of specific bacterial genera in the gut microbiota, as well as alterations in microbiota-derived metabolites, has been identified as a potential key factor in the pathogenesis of IBD (28, 29)

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