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That number0.08%is an important one: there is no state in which a person can legally drive with a BAC over 0.08% (although some have enhanced penalties for even higher BACs)

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It reflects the biochemistry of copper peptides in solution

There are many potential/partial explanations for this difference: Tirzepatide is a dual agonist (for GIP/GLP-1), making it an arguably more structurally complex molecule and less tenable for recombinant expression (though both are linear peptides with a side chain)

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Rybelsus delivers approximately 45%, but offers the significant advantage of no injections