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GIP (glucose-dependent insulinotropic polypeptide) enhances insulin secretion and influences fat metabolism, and there is evidence that it actually softens some of the GI side effects that come from GLP-1 stimulation

No participants developed antibodies against the peptide, and no serious adverse events led to treatment withdrawal

Illustrative Cases High Triglycerides: A 58-year-old man with poorly controlled diabetes (A1c 9.2%) and moderate triglyceride elevation started semaglutide

This is invasive and not always accessible, leading to severe diagnostic delays estimated to be between 4 to 11 years and a massive underestimation of disease prevalence

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