The expanded panels continue to focus on drugs of abuse, not research compounds
After adjusting for potentially influential factors including age, sex, ethnicity, pre-existing conditions, other medication use, and body mass index, use of GLP-1 receptor agonists was associated with a 37% higher risk of alopecia than use of SGLT-2 inhibitors (6.91 v 5.04 per 1,000 person years) and a 68% higher risk than use of DPP-4 inhibitors (6.53 v 3.89 per 1,000 person years)
That trajectory is plausible given the mechanistic evidence, though individual responses vary considerably depending on eczema severity, trigger profile, genetic factors, and concurrent treatments
This gives you the confidence that your results are based on the actual compound you intended to study
Still, optimal results are obtained when breast milk is alternated with a Phe free infant formula as this results in long-term satisfactory control of Phe levels and growth [68,69,70]
Yes, when taken in recommended doses under medical guidance, they are generally safe for daily use
