Variants in genes affecting glutathione metabolism, oxidative stress responses, and metabolic inflammation may help provide context for why certain patients respond more robustly to supplementation strategies
Although selenium supplementation demonstrates potential benefits in reducing autoantibody levels, the existing body of researchprimarily limited to short-term observations of 36 monthsfails to establish a definitive causal relationship between decreased antibody titers and sustained functional improvements in the neurological system (264)
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Zheng J, Wang S, Xia L, Sun Z, Chan KM, Bernards R, et al
Biomed Technol 5:109122
Moreover, emerging evidence supports the potential of adjunctive interventionssuch as melatonin, tocotrienol, colchicine, and magnetic field therapyas complementary strategies to conventional antiresorptive and anabolic treatments