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Somatic mutations in specific and connected subpathways are associated with short neuroblastoma patients survival and indicate proteins targetable at onset of disease
It drives neuronal mitochondrial biogenesis through CREB-PGC-1 signaling, a pathway that can bolster cellular resilience to stress
Reaching a goal is one milestone
None of it is definitive at the human clinical level
Physicians must also consider FDA law and malpractice insurance coverage
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