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FIGURE 1 The transition of metal ions valence would also be a powerful strategy for GSH exhaustion

2017;68:224e224

doi: 10.1371/journal.pone.0269282 41 HongYNamDYangCKangBKKimARShinKMet al

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Both inflammation and apoptosis are involved in cartilage homeostasis, and therefore OA, which seem to be regulated by miRNAs [50, 51]

or are both caused by insulin resistance