This observation is probably consistent with release of insulinotropic hormones during ingestion of all three macronutrients
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All participants received oral NAC 600-mg uncoated tablets, which were administered first as a single dose and, following a 48-h wash-out period, twice daily for 3 days
( ad ) Mean (SE) change from baseline in fasting free fatty acids, n = 68 for AMG 133 and n = 6 for placebo at Day 1 (A), fasting triglycerides, n = 6 for AMG 133 and n = 6 for placebo at Day 1 (B), fasting total cholesterol, n = 68 for AMG 133 and n = 6 for placebo at Day 1 (C), fasting LDL, n = 6 for AMG 133 and n = 6 for placebo at Day 1 (D) after multiple ascending doses of AMG 133 or placebo
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