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doi: 10.3389/fendo.2024.1503905 Received 29 September 2024 Accepted 09 December 2024 Published 09 January 2025 Volume 15 - 2024 Edited by Weibin Bai, Jinan University, China Reviewed by Zia Ur Rehman, University of Agriculture, Pakistan Kamil Gill, Pomeranian Medical University, Poland Updates Copyright 2025 Saleh, Sallam, Elsuity, Dutta, Sengupta and Nasr

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To view a copy of this licence, visit About this article Cite this article Ahmad, N., Lesa, K.N., Ikawati, Z

When the ovaries produce estrogen, some of it is metabolized in the liver, while the rest makes its way to the gut in the form of estrogen byproducts