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Conformational change in the active center region of GST P1-1, due to binding of a synthetic conjugate of DXR with GSH, enhanced JNK-mediated apoptosis
Studies have shown that it can reduce the release of pro-inflammatory factors by inhibiting the NF-B and COX-2 pathways, and activate Nrf2 to enhance the activity of antioxidant enzymes (45)
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A study conducted on a mouse model of colitis found that the GLP-1RA liraglutide significantly improves IBD activity
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