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Organosulfur compounds, including allicin, DAS, DADS, DATS, ajoene, and SAMC, have been found to induce cell cycle arrest when added to cancer cells in cell culture experiments (reviewed in 4, 70)

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By contrast, the stress sensor GADD45 was detected within only early differentiating IRS cells (supplementary figure 3c), while the ROS-protective protein heme oxygenase-1 (HO-1) was intensely expressed in a small subset of IRS cells located usually in the upper follicle, at the level of the sebaceous gland, where IRS cornification is advanced to complete (supplementary figures 3g and 3h)

In 1998, W McNeely reported the use of oral coumarin combined with ultraviolet A (UVA) exposure in patients with vitiligo [151]