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The incidence of markedly low serum potassium (less than 3 mEq/L, and a reduction from pretreatment of greater than 0.5 mEq/L) at any time during the trial was 0.2% for phentermine and topiramate extended-release 7.5 mg/46 mg dose and 0.7% for phentermine and topiramate extended-release 15 mg/92 mg dose, compared to 0% for placebo

Exposure to extreme temperatures can damage the drug and make it less effective

A study showed that changes in postprandial GLP-1 RA levels were positively correlated with local cerebral blood flow to the left dorsolateral prefrontal cortex and the hypothalamus, which is known to be associated with satiety and the control of food intake [5]

Be vigilant for new or worsening symptoms

Each iv therapy session is overseen by a physician and administered by a licensed nurse

This combination activates the cAMP PKA signaling pathway, triggering a series of metabolic reprogramming events