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PMID: 11162489

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The pharmacokinetic and tissue-distribution profile of the compound has been characterized at varying levels of detail across the different research contexts

Double mutant embryos exhibit normal initial development of VTA DA neurons, followed by complete caspase-dependent apoptotic loss by embryonic day 14 ( During VTA DA neuron differentiation, Lmx1a and Lmx1b are co-expressed in VTA DA neural progenitors and function as critical mediators of early DA specification (Zou et al., 2009)

References Detcheverry F, Senthil S, Narayanan S, Badhwar A