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doi: 10.1016/j.bbi.2024.04.005 45 MiYQiGVitaliFShangYRaikesACWangTet al

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Under normal conditions, an enzyme system (NADPH-dependent methemoglobin reductase) keeps methemoglobin levels low, but if this system is overwhelmed (by oxidant drugs or toxins), MB administered intravenously acts as an artificial electron carrier

Limn-Pacheco JH, Gonsebatt ME (2010) The glutathione system and its regulation by neurohormone melatonin in the central nervous system