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10.3390/bioengineering6010022 Bioengineering 9 Di MiccoR.KrizhanovskyV.BakerD.DaddaDi FagagnaF

Here, we describe the potential mechanisms underlying how statins affect glucose homeostasis

Cognitive function, assessed by the MMSE and clock test, and mood, measured by the GDS-15, were evaluated at baseline and study end

Eur J Pharmacol 332: 2333

Mechanistically, glutamine limitation decreases GSH levels and sarco/endoplasmic reticulum Ca 2+ -ATPase (SERCA) glutathionylation, resulting in reduced SERCA activity 58

After that, primary human hepatocytes were exposed to rhHMGB1 for 24 hours at 300 ng/ml (concentration measured in the supernatant of HepaRG cells APAP-treated as shown in Fig