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doi: 10.1126/science.adh8488

Blood 124 , 2256 (2014)

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Figure 1 4.1.2 Reducing fatigue in the central nervous system Reducing fatigue in the central nervous system is an important mechanism for enhancing physical performance, with its core focus on regulating the levels of neurotransmitters (such as 5-HT, norepinephrine, and dopamine) and neuromodulators (such as adenosine) to maintain arousal, attention, and motivation during exercise (131)