Despite growing evidence that GLP-1 medications improve health and are worth their cost, many insurance plans still limit coverage
2023;19:S21
The most common side effects are gastrointestinal, including nausea, vomiting, and diarrhea
Oral semaglutide versus subcutaneous liraglutide and placebo in type 2 diabetes (PIONEER 4): a randomised, double-blind, phase 3a trial
Routine monitoring typically includes : HbA1c measurements every 3-6 months to assess long-term blood glucose control Renal function tests (eGFR and urine albumin-to-creatinine ratio), as diabetes can affect kidney function Blood pressure monitoring , as hypertension commonly coexists with type 2 diabetes Lipid profile assessment to manage cardiovascular risk Body weight tracking , as Rybelsus often leads to modest weight reduction Patients with pre-existing diabetic retinopathy should be particularly vigilant, as rapid improvements in glucose control with GLP-1 receptor agonists may temporarily worsen retinopathy
A seminal study by Zander et al
