With a growing number of patients using these medications for diabetes or to meet certain optimization goals before undergoing hip and knee reconstructive surgery, our aim was to establish evidence-based guidelines on when to discontinue these to enhance patient safety and surgical success. The study, Optimal Timing for Cessation of GLP-1 Agonist Before Elective Total Hip and Knee Arthroplasty, obtained data from the TriNetX Research Network, a multi-institutional national aggregated database, to identify patients who underwent TKA or THA from January 1, 2018 to January 1, 2023
Used alongside nutrition and lifestyle guidance, they support sustainable weight loss under medical supervision
There is now growing appreciation that renal impairment can develop in people with diabetes in the absence of increasing albuminuria and in the presence of other nondiabetes-related causes of CKD
This local presence supports community members on their weight loss journey, fostering a supportive environment
Amylin, an anorexic neuroendocrine hormone co-secreted with insulin, is deficient in individuals with diabetes and plays an important role in postprandial glucose homeostasis, with additional potential cardiovascular and neuroprotective functions
The fiber's role in promoting a feeling of fullness can occasionally lead to such symptoms, particularly if your body isn't accustomed to high fiber intake