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In the Phase 2 trial, body composition was assessed using dual-energy X-ray absorptiometry (DEXA) in a subset of participants

The functional consequence in animal models is synergistic rather than additive GH output: GHRH-R priming increases the pool of releasable GH vesicles, and GHS-R1a co-stimulation then drives a larger amplitude pulse than either receptor produces alone

Severe cases may cause fainting (syncope), which requires immediate medical evaluation

When administered in either way, the digestive system is completely bypassed allowing for full absorption

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