How to Mitigate Side Effects from GLP-1 Medications: GI Upset and Muscle Loss The complete list of side effects of GLP-1 drugs is still ongoing, however, one thats spoken about most often is gastrointestinal side effects
28.3% weight loss in Phase 3 at 80 weeks
Lifestyle integration protein targets, resistance training, sleep, alcohol limits
Main similarities and differences in the effects of GLP-1 and GIP GIP and GLP-1 are incretin hormones with a common primary effect of stimulating insulin secretion in response to food intake, but with significant differences in additional physiological effects, particularly with regard to the regulation of glucagon secretion, effects on appetite and lipid metabolism, and bone metabolism
Here is how to think about it: What is normal during titration Mild nausea that comes and goes, especially in the first 35 days after a dose increase Reduced appetite this is the medication working as intended Occasional loose stools or minor constipation Mild fatigue or low energy as your caloric intake decreases Slight bloating or feeling full faster than usual These effects are typically self-limiting
Metformin and Ozempic both commonly have digestive side effects, including abdominal pain, heartburn, nausea, vomiting, diarrhea, and constipation