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Tau has been shown to reduce secondary brain injury after CI by down-regulating the expression of matrix metalloproteinases-3 (MMP-3) in brain-injured rats, thereby protecting the BBB ( Furthermore, investigation revealed that BC and its active constituents, including Tau, TUDCA, and UDCA, can decrease lactate dehydrogenase levels, increase -GT content, raise TEER values, and decrease fluorescein sodium permeability coefficient

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Vitamin shots that include B12 are commonly used as a general wellness treatment to combat tiredness and support overall metabolic health

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Future research should define precise reference ranges and validate supplementation efficacy through rigorous trials