Hemorrhagic transformation occurs through a disruption in tight junction proteins, and investigations into this underlying mechanism found that dysregulated extracellular proteolysis in the vascular matrix after tPA contributes to hemorrhagic transformation (Chandler et al., 1990
Acta (BBA) - Mol
The "Glow" blend is synthetically manufactured, allowing precise control of sequence fidelity and molecular structure
Methods: Retrospective, single-center study including consecutive ESUS patients admitted from January-2016-to-May-2024
Disclosure of interest: Xinjie Gao: nothing to disclose Poster Session I - INTRACRANIAL HEMORRHAGE 02.00 - INTRACRANIAL HEMORRHAGE - 02.01 - INTRACEREBRAL HAEMORRHAGE P158 - ESOC25-1869 ACCURACY OF AUTOMATED HEMORRHAGE SUBTYPE DETECTION IN SUSPECTED INTRACEREBRAL HEMORRHAGE James Garrard 1,2 , Artem Kaliaev 3 , Asim Mian 3 , Chad Farris 3 , Pau Bellot 1 , Olivier Joly 1 , Zoe Woodhead 1 , James Briggs 1,4 , Davide Carone *1 , George Harston 1,2 , Mohamad Abdalkader 3 1 Brainomix, OXFORD, United Kingdom, 2 Oxford University Hospitals, OXFORD, United Kingdom, 3 Boston Medical Centre, Boston, United States, 4 Royal Berkshire Hospital, Reading, United Kingdom Background and Aims: Early identification of patients with intracerebral hemorrhage (ICH) is thought to be critical to improve outcomes through earlier implementation of evidence-based care-bundles