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Unopposed antidepressant therapy is known to lead to manic switch in a modest proportion of bipolar disorder patients (Gorwood et al., 2016), but this does not occur in the context of a mood-stabilizer or neuroleptic use (Post et al., 2003), with attention being paid to the subgroup of patients susceptible to antidepressant-induced manic switch
Asian J Psychiatry
the metabolic profiles of schisantherin A were investigated in vitro (rat liver microsomes) and in vivo (rat plasma, urine, and bile) via UPLCQ-TOFMS/MS
At times, patients have accidentally injected five to 20 times more than the intended dose of semaglutide (!)
Serious side effects are very rare and monitored for during treatment