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Extracellular NAD + can enter cells via pore-forming channel connexin 43 (Cx43), a bi-directional NAD + transporter allowing exogenous NAD + transportation into the cell, and transportation out for utilization of NAD + by CD38 64

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Mol Cell Biol (2012) 32(5):100416.10.1128/MCB.06252-11 89 PeverelliEGiardinoETreppiediDVitaliECambiaghiVLocatelliMet alFilamin A (FLNA) plays an essential role in somatostatin receptor 2 (SST2) signaling and stabilization after agonist stimulation in human and rat somatotroph tumor cells