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Some individuals notice vivid dreams, lighter sleep, or difficulty adjusting as their circadian system responds to the peptide's effects on melatonin regulation

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In clinical trials for Ozempic, gastrointestinal side effects like nausea, vomiting, and diarrhea were commonly reported

However, a slight increase in OCD risk was observed, and no significant associations were identified for broad depression, major depressive disorder, anorexia nervosa, or self-harm

Dipeptidyl peptidase-4 inhibition with saxagliptin enhanced nitric oxide release and reduced blood pressure and sICAM-1 levels in hypertensive rats