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Co-formulation approaches such as SNAC address stability and absorption at the site of dosing, shaping how the molecule reaches circulation

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10.1016/S2213-8587(13)70113-X 50 HeJ.ChuY.LiJ.MengQ.LiuY.JinJ.et al (2022)

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9-13 There are also GLP-1 and GIP receptors in the central nervous system, and their binding suppresses appetite and increases the sensation of being full