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To reveal the expression profile and functional evolution of the carnitine pool in different disease states, and how these changes profoundly affect the disease process, the effect of treatment, and the response of patients to treatment

The combination strategy demonstrated the effectiveness of CB-839 treatment in cetuximab-sensitive and cetuximab-resistant models (Lu et al., 2021

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Studies show it can significantly lower inflammatory signaling and neutrophil activity in models of acute inflammation ( Getting et al., 2003, J Pharmacol Exp Ther ), while broader reviews highlight its potential as a non-pigmenting, anti-inflammatory peptide for skin and gut repair ( Brzoska et al., 2008, Endocr Rev )

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