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In cancer, circadian disruptiontriggered by irregular light exposure or shift workhas been linked to increased tumor risk and progression, partly due to dysregulation in clock-controlled ubiquitin-mediated degradation of oncogenes and tumor suppressors such as p53 (Reszka and Zienolddiny, 2018

[DOI] [PubMed] [Google Scholar] 77.Vaux E.C., Taylor D.J., Altmann P., Rajagopalan B., Graham K., Cooper R., Bonomo Y., Styles P

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Briefly, glutathione status has been favorably linked to two well-established redox sensitive transcription factors, nuclear factor B (NK-B) and activator protein-1[19, 20]

Circadian Rhythm Disruption Promotes Lung Tumorigenesis

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