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This loss of myelin is associated with reduced axon conduction, an increase in the metabolic cost of action conduction, and an increased vulnerability of axons to inflammatory and oxidative injury (56)

patients should be counseled about the potential risk for MTC with use of this drug and should be informed of symptoms of thyroid tumors (e.g., a mass in the neck, dysphagia, dyspnea, persistent hoarseness)

Cardiovascular & Renal Benefits of GLP-1 Receptor Agonists Meta-analysis (2024) comprehensive review showing GLP-1RAs reduce major adverse cardiovascular events (MACE), all-cause mortality, stroke, and kidney-related outcomes, in patients with and without diabetes

Human cancer develops through diverse genetic, environmental and age-related pathways that cannot be represented by a single mouse model

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