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Moreover, over 40% of people who start taking GLP-1s quit the medicines within 2 years due to high costs and gastrointestinal side effects such as nausea, diarrhea, vomiting, and constipation, according to a study published in JAMA Network Open last year

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It is one of the most widely studied "body protection" peptides in the preclinical literature

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These in vitro findings highlight that even within the same class of drugs, subtle differences in how they interact with their target receptors can exist, which may translate to different overall effects in the body

This makes them appealing to those dealing with injuries, inflammation, or chronic health issues