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3 Nutritional vigilance, including appropriate dietary counseling and targeted supplementation, is fast becoming a cornerstone of responsible GLP-1based care

Among them, the membrane surface FSP1CoQ10 system can effectively block the lipid radical chain reaction by maintaining ubiquinol or CoQ10H 2 levels in the lipid membrane region, while mitochondrial inner membrane DHODH exerts local antioxidant effects by regulating the redox state of mitochondrial CoQ/CoQH 2 (Mao et al., 2021)

2.1.1.2 Apoptosis, immune cells and intestinal barrier integrity In crypts of affected and nearby uninvolved regions, apoptosis is the primary cause of epithelial cell death in active UC, with the Fas/Fas-L relationship acting as a mediator (59)

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