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She had radicular left lower-extremity pain on movement, which worsened over the course of a year, evolving into a chronic neuropathic pain with a breakthrough component

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While initial weight loss may be substantial for many patients in early months, a plateau does not necessarily indicate medication ineffectiveness

Neuroleptics and operant behavior: the anhedonia hypothesis

Patients were randomly assigned to L-carnitine (510 mg/day), followed by placebo or vice versa