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There are other reasons such as iron deficiency and thyroid dysfunction that may lead to symptoms similar to sub-optimal B12 levels

Oncogenesis 10 , 66 (2021)

2- NSAIDs: show no statistically significant pain relief compared to placebo in osteoarthritis patients

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References Kolomin, T., Shadrina, M., Slominsky, P., Limborska, S., & Myasoedov, N