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Sources Wu, G., Fang, Y

However, as detailed above, cells that exhibit higher levels of mitochondrial activity are less sensitive to 5FU treatment, and those with compromised mitochondrial function are more sensitive, correlating with intrinsic resistance

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doi: 10.1002/jmv.27405 181 MarM.de GregorioE.de DiosC.Roca-AgujetasV.CucarullB.TutusausA.et al