PMID: 2155033 DOI: 10.1016/S0006-3495(90)82574-1 Crumb WJ Jr, Clarkson CW (1992): Characterization of the sodium channel blocking properties of the major metabolites of cocaine in single cardiac myocytes
Pharmacokinetics: Well absorbed following oral administration (half-life: 3-4 hours) Hepatic metabolism Adverse Effects: absence of liver failure
Con: IV is more invasive with a needle into your blood vessels, and many people may not find the experience pleasant
Unfortunately, about 10 percent of those infected even those with only mild or no symptoms initially, suffer long after the usual two-week recovery period and even after theyve tested negative for the virus
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Moving forward, however, translating this approach to mammalian systems requires the strategic integration of feedback-responsive materials that harmonize with, rather than disrupt, complex endogenous regulatory mechanisms
