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Here, we discovered that some of the NE in cecal contents is derived from the sympathetic nerves of the host because the liraglutide-induced NE increase was unaffected by adrenalectomy but suppressed by chemical sympathetic nerve blockade
(2025) doi: 10.1001/jamapsychiatry.2024.4789 Summary Keywords alcohol use, All of Us cohort, cocaine dependence, drug repurposing, GLP-1 receptor agonists, nicotine dependence, opioid use, substance use disorders Citation Abegaz TM, Ahmed M, Bhagavathula AS and Frietze G (2026) Association between GLP-1 receptor agonist use and substance use disorders among individuals with type 2 diabetes or obesity: a nested case-control study in the All of Us research program
Results showed improvement in GI motility endpoints with an acceptable safety profile
Summary of product characteristics (Trulicity)
Your healthcare team will arrange appropriate antenatal monitoring, provide reassurance, and help you report the exposure to the MHRA Yellow Card Scheme to contribute to safety data