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The level of KEAP1 mRNA was shown to be increased in the motor cortex but not in the spinal cord of ALS patients compared to controls

However, the rising prevalence of depression in the general population is coupled with an increasing number of patients who do not respond to antidepressant therapy, underlining the need to identify underlying factors to enable early detection and intervention, especially in high-risk groups [498]

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L.DenkelK.et al (2023)

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These changes show how the body handles certain substances differently