Importantly, signs of ER dysfunction identified in our proteomics dataset might contribute to broader changes in cellular function, as suggested by previous studies on glycosylation changes in chondrocytes under inflammatory stimuli, particularly involving sialic acids
The balance between eumelanin and pheomelanin influences skin tone
doi: 10.1074/jbc.M601876200
Therapeutic implications Identifying the genes regulating GSH levels in RBCs and possibly other tissues will be very important for clinical use of our finding
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The genetic and metabolic signature of oncocytic transformation implicates HIF1alpha destabilization
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