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Decreased production has been associated with motility dysfunction and delayed gastric emptying in humans

Upon sensing environmental stress or cellular damage, the absent in melanoma 2 inflammasome (AIM2) and NLR family pyrin domain-containing 3 (NLRP3) inflammasome assemble and recruit the inflammasome adapter protein apoptosis-associated speck-like protein containing CARD, leading to the activation of pro-inflammatory caspases [137]

One experienced practitioner noted that the peptide works well for acute soft tissue injuries but fails at chronic structural damage

once reconstituted, use promptly under sterile lab conditions

10.1007/s004310051054

If your symptoms do return, you may be able to have a repeat injection but its not always effective