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In diabetes-related AD, GLP-1 promotes mitochondrial biogenesis and the antioxidant system by regulating the PGC-1a signaling pathway in vivo to directly reverse tau hyperphosphorylation

IF increases HDL by enhancing the synthesis of apoprotein A (ApoA) and downregulating cholesteryl ester transfer protein (CETP)

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The region benefits from a high prevalence of obesity and type 2 diabetes, advanced healthcare infrastructure, substantial pharmaceutical research and development investments, favorable reimbursement frameworks, and rapid adoption of innovative therapeutic technologies

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