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De Filippis F, Pasolli E, Tett A, Tarallo S, Naccarati A, De Angelis M, Neviani E, Cocolin L, Gobbetti M, Segata N, Ercolini D

A person with lupus might be more likely to benefit from discussing a GLP-1 medicine with their clinician if they have: Type 2 diabetes Obesity or overweight with weight-related health problems High blood pressure High cholesterol Fatty liver disease High cardiovascular risk Kidney risk factors Difficulty losing weight despite serious lifestyle efforts These medicines may be especially worth discussing when weight, diabetes, or cardiovascular risk is making lupus care more difficult

Both drugs can also cause more serious side effects

Glutathione is often referred to as the master antioxidant. Its a powerful molecule made up of three amino acids: cysteine, glutamine, and glycine

doi: 10.1046/j.1468-2982.2002.00412.x 84

13 C-glucose labeling into TCA cycle intermediates was elevated in ACLY KO and DKO cells despite modest to no change in abundance of these metabolites (Figure 5E, Supplemental Figure 5F)