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Accessed 8/12/2015

Gray, Kaye H

A gene expression signature in HER2+ breast cancer patients related to neoadjuvant chemotherapy resistance, overall survival, and disease-free survival

Pathogenesis of multiple system atrophy (MSA), characterized by a variable combination of parkinsonism, cerebellar impairment, and autonomic dysfunction, is ascribed to the accumulation of aggregated -synuclein in OLs, which leads to severe neuronal loss, yet only a modest reduction in OLs 20,21

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While individual responses can vary, most patients report visible improvements within 6-12 weeks of consistent treatment