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doi: 10.1038/oby.2003.128
showed that enhanced GLUT4 translocation increases Akt phosphorylation in adipocytes, further boosting a critical pathway in the insulin signaling cascade (Gemma et al., 2010b
doi: 10.1016/S0026-0495(99)90013-6 39 AlesciSManoliICostelloRCoatesPGoldPWChrousosGPet al
Cell Mol Life Sci (2020) 77:372943
Predictive toxicology to flag potential immune responses
This severe metabolic inflexibility directly contributes to the debilitating phenomenon of post-exertional malaise (PEM), where patients experience a massive, multi-day crash in symptoms following minor physical or cognitive exertion, effectively trapping them in a cycle of energy debt
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