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ASCs may choose to: (1) directly submit their PRO-PM data to CMS using the HQR system

A 6 mm needle may be adequate for lean individuals with thin subcutaneous layers, while those with greater adipose tissue may benefit from slightly longer needles to ensure reliable subcutaneous placement

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Clinical experience from practitioners treating MCAS and histamine intolerance adds human evidence, though formal clinical trials for allergic conditions specifically are still needed