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In the realm of type 2 diabetes and obesity, GLP-1 receptor agonists have also provided evidence for the ability of peptides to cross the BBB

Furthermore, a network meta-analysis examining the effects of GLP-1 RA therapy on body composition reported a greater reduction in lean body mass in the intervention group compared with placebo or active comparators (mean difference = 0.86 kg, 95%CI: 1.30, 0.42)

Mol Cell Endocrinol 2009

While no SAEs were seen in our cohort, some complained about mild gastrointestinal AEs

The medication is still working

Suddenly, people without diabetes started clamoring for a piece of the Ozempic action