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Further well-designed, multicenter randomized controlled trials employing standardized and sensitive apnea detection methods are essential to definitively evaluate this potential application (45, 78)
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Niflumic acid is also a TRPV1 channel antagonist and it was reported that peripheral neuropathy by suppressing excessive ROS, RNS, inflammatory cytokine production and TRPV1 activation in neuropathic pain-induced rats were recovered by the niflumic acid treatment (Marwaha et al., 2016)
leaves as a source of bioactive compounds of pharmaceutical interest