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Two-hour insulin: Five studies (218 participants) were pooled for the analysis of change-from-baseline two-hour insulin levels (Electronic Supplementary Fig

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The induction of diabetes and CKD using STZ and adenine, respectively, in the experimental animals resulted in significant hyperglycemia, weight loss, polyuria, impaired renal function and structure, and increased oxidative stress accompanied by a compromised antioxidant defense system and dysregulated inflammatory markers

Vukojevi, J., et al

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