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Future research should focus on identifying heterogeneous treatment effects specifically, determining which patients are most likely to benefit and who may be at greater risk for safety concerns, Guo said.

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What studies show: In a 72-week trial of adults with obesity, once-weekly tirzepatide at 5 mg, 10 mg, and 15 mg led to average weight loss of 15.0%, 19.5%, and 20.9%, respectively, compared with 3.1% with a placebo

Our data also showed positive correlations between C56:4 and C57:4, both containing C18:2 and C16:0, with SC adipogenic capacity